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Mass Spectrometry Standards Working Group Charter

Submitted: 2025-06-17
Template Rev2016b

1.Administrative Section

Status (New/Update): Update

Group Name: Mass Spectrometry Standards Working Group (PSI-MS WG)

Chair (with affiliation and current email address):
Eric Deutsch, Institute for Systems Biology (edeutsch@systemsbiology.org)

Co-Chairs (1 or 2) (with affiliation and current email address):
Pierre-Alain Binz, CHUV Centre Hospitalier Universitaire Vaudois (Pierre-Alain.Binz@chuv.ch)
Henry Lam, Hong Kong University of Science and Technology (kehlam@ust.hk)

Secretary:

<position is currently unfilled>

Other officers (optional) (with affiliation and current email address):

Editor(s):

<position is currently unfilled>

Minimal Reporting Requirements Coordinator(s):

Pierre-Alain Binz, CHUV Centre Hospitalier Universitaire Vaudois (Pierre-Alain.Binz@chuv.ch)

Ontology Coordinator(s):

Joshua Klein, Boston University (jaklein@bu.edu)

Web site Maintainer(s):

<position is currently unfilled>

Mailing list:

psi-ms-dev@lists.sourceforge.net

2.Description and objectives

Focus and Purpose

The PSI-MS working group is composed of academic, government, and industry researchers, software developers, journal representatives, and instrument manufacturers. The main goal of the PSI-MS working group is to define community data formats and associated controlled vocabulary terms, facilitating data exchange and archiving of mass spectrometry raw data and other data needed as input to informatics analysis.

Current projects of the PSI-MS working group are:

  • Completion of the mzPAF format
  • Completion of the mzSpecLib format
  • Completion of the ProForma 2.1 format
  • Enhancement of the mzML format for IMS and DIA data
  • Development of the mzPeak format as a replacement for mzML
  • Further development of PROXI
  • Maintenance and enhancement of the PSI-MS controlled vocabulary

Goals/Milestones

Goal 1: Ratification of the mzPAF peak annotation format. This standard is currently in the Document Process and will be finalized as an official PSI specification in 2025.

Goal 2: Ratification of the mzSpecLib format. This standard is currently in the Document Process and will be finalized as an official PSI specification in 2025.

Goal 3: Ratification of the ProForma 2.1 format. This standard is currently being developed and will enter the Document Process in mid-2025.

Goal 4: Finalize the mzML for ion mobility and DIA data best practices document. This standard is currently in the Document Process and will be finalized as an official PSI specification in 2025

Goal 5: Work with the community to define a next-generation faster and smaller MS run format, currently envisioned as a format based on the Parquet technology and tentatively name mzPeak. A journal article describing its goals and plans will be published and exploratory software will be written to test the performance of envisioned functionality.

Goal 6: We will continue to develop the PROXI web services definition, with an aim to release a mature version 1.0 specification, along with a publication in 2026.

Websites:

http://www.psidev.info/groups/mass-spectrometry

http://www.psidev.info/mzPAF

http://www.psidev.info/mzSpecLib

http://www.psidev.info/mzML

http://www.psidev.info/PROXI