Quality Control

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HUPO Proteomics Standards Initiative
Quality Control Working Group (PSI-QC)


  1. Quality Control Group Charter
  2. Group Structure (2017)
  3. Formats, Definitions, and Metrics
  4. Getting Involved


The PSI Quality Control workgroup is one of the working groups of the Proteomics Standards Initiative.


Quality Control Group Charter

Focus and Purpose

The PSI-QC working group is composed of academic, government, and industry researchers, software developers, journal representatives, and instrument manufacturers. The main goal of the PSI-QC working group is to define a community data format and associated controlled vocabulary terms, facilitating data exchange and archiving of mass spectrometry derived quality control metrics.

Current projects of the PSI-QC working group are:

  • The qcML format, which has been developed as a standardized format for the exchange, transmission, and archiving of quality control metrics derived from mass spectrometry.
  • Controlled Vocabulary development: controlled vocabulary terms are developed in common with the PSI-MS and PSI-PI groups.


  1. submit a perspective manuscript to a journal in the field to announce the PSI-QC WG  (PubMed link)

  2. analyze and revise the already published qcML format for submission to the PSI document process √ 

  3. re-evaluate the CV terms used for qcML, and consolidate the location for these terms in light of the existing PSI-MS CV √ 

  4. adapt the already published jqcML library to handle the updates to qcML and the CV terms; implement validation

  5. implement qcML output from several freely available quality metric tools (e.g., QuaMeter, OpenMS)

  6. establish the revised qcML format and associated CV terms as a HUPO-PSI standard, by submitting the standard to the PSI Document Process



Group Structure (2017)

Current Incumbent
Chair David L. Tabb
Co-chair Mathias Walzer, Wout Bittremieux
MIAPE Co-ordinator Weimin Zhu, Reza Salek
Ontology Co-ordinator Julian Uszkoreit
Editor Stefan Tenzer
Secretary Wout Bittremieux
Website Maintainer Mathias Walzer
MaxQuant liaison Chris Bielow


Formats, Definitions, and Metrics

You can find the ongoing work and older versions of the qcML format, term definitions, and metric designs on our HUPO-PSI GitHub page.

Getting Involved

If you would like to contribute to the work of the Quality Control workgroup, or just to receive the occasional email when a new version of a format becomes available, please contact us on psidev-qc-dev [at] lists.sourceforge.net or our GitHub page.