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HUPO-PSI Spring Meeting 2025

The next HUPO-PSI Spring Meeting will take place at the University of Tuebingen, Germany from March 31st-April 3rd. The event will kick off with two days of hands-on workshop sessions on the use of machine-learning in MS-based proteomics, interactions and related areas.

Documents in progress and new documents

  • The mzQC format, a data standard for reporting and exchanging quality-related information in biological mass spectrometry, has been been released on February 21st, 2024
  • The mzIdentML 1.3.0 specification and its crosslinking extension have been released on July 4th, 2024.
  • mzSpecLib in anticipation of becoming formal standard

See more details on these documents in progress.

HUPO-PSI Working groups and Outputs

The HUPO Proteomics Standards Initiative defines community standards for data representation in proteomics and interactomics to facilitate data comparison, exchange and verification.

Working Groups Guidelines v. Formats v. Controlled Vocabularies  v.

Molecular
Interactions
Group charter

MIMIx
MIABE
MIAPAR

1.1.2
1.0.0
1.0.0

PSI-MI XML
PSI-MI XML
MITAB

2.5.4
3.8.8
2.8

PSI-MI CV 

2.5.0

Mass Spectrometry
Group charter

 

Proteomics Informatics
Group charter

Mass spectrometry (MIAPE-MS) 
Identification (MIAPE-MSI)
Mass spectrometry Quantification (MIAPE-Quant)

2.98
1.1
1.0

mzML
TraML 
mzData
mzIdentML 
mzQuantML* 
mzTab
mzTab-M
proBed 
proBAM 
PEFF 
USI
SDRF-Proteomics
mzSpecLib (in development)
ProForma

1.1.0
1.0.0
*
1.3.0
1.0.0*
1.0.0
2.0.0

1.0.0
1.0.0
1.0.0
1.0.0
1.0.0
1.0.0
1.0.0

PSI-MS 
XLMOD 

4.0.15
1.1.0

Quality Control
Group charter
    mzQC 1.0.0    
Disordered Proteins
Group charter
Minimum Information About Disorder Experiments (MIADE) 1.0         
Protein Separation
(Inactive)

Gel electrophoresis (MIAPE-GE) 
Gel informatics (MIAPE-GI) 
Column chromatography (MIAPE-CC) 
Capillary electrophoresis (MIAPE-CE) 
Phosphoproteomics (MIASSPE) 

1.4
1.0
1.1
0.9.3
0.9

GelML 
spML 
1.1.0
1.0.0
sepCV  1.0.0

* deprecated