The Molecular Interactions workgroup is concentrating on:
- improving the annotation and representation of molecular interaction data wherever it is published, be this in journal articles, authors web-sites or public domain databases
- improving the accessibility of molecular interaction data to the user community. By using a common standard data can be downloaded from multiple sources and easily combined using a single parser
To this end we have developed :
Minimum Requirements Standards
- MIMIx - the Minimum Information about a Molecular Interaction experiment guidelines to assist the scientist in reporting and submitting interaction data and in manuscript preparation (Full text)
- MIAPAR - the Minimum Information about a Protein Affinity Reagent to assist the scientist in describing reagent, such as antibodies used as protein identification tools (full text).
- MIABE- Minimum Information About a Bioactive Entity guidelines to assist the scientist in reporting and submitting drug-target data
Data exchange formats and Controlled vocabularies
- PSI-MI XML v2.5 data interchange format (the deprecated version 1.0 is still available here, with some details on how to convert files from 1.0 into 2.5 version)
- MITAB data interchange format, a common tab delimited format.
- PSI-PAR Representation of Protein Affinity Reagents (PARs) in the PSI-MI XML format
- PSI-MI CV the controlled vocabularies for annotating the data in combination with the PSI-MI XML format
- PAR CV the controlled vocabularies for annotating the data in combination with the PSI-PAR XML format
Tools
- A PSI-MI validator stand alone tool, checking that files compile using the XML format and the CVs are compliant to the MIMIx guidelines
- PSIQUIC a web service to access the interaction data